That load may be way too hot for your revolver
The reason I say this is that if you check the Hodgdon and Hornady reloading books, such a load in 45 Colt is only safe in Ruger, Freedom Arms, and T/C handguns. I shoot a 300 gr. XTP behind 22 gr. of H110 in my 45 Colt Ruger Blackhawk with a 7" bbl. for about 1150 FPS. Pretty wicked load.I have also shot 300 gr. XTPs out of my S&W 629 Classic with a 5" bbl. with 19 gr. of H110 getting about 1200 FPS.With both of these loads I am starting to see some slight flattening out of the primers indicating STOP HERE
and back off a little. Even at this point I have no extraction problems. These loads are from Hodgdon.JMHO. Be safe.